PCAF, SIRT1 and the regulation of substrate acetylation
<p>Levels of lysine acetylation (KAc) in cells are regulated by epigenetic enzymes with opposing roles; histone acetyl transferases (HATs) and histone deacetylases (HDACs). The HAT p300 CBP associating factor (PCAF) and the sirtuin HDAC SIRT1 have protein substrates in common, including histon...
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| Format: | Thesis |
| Language: | English |
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2021
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