Novel function of CRTH2 in preventing apoptosis of human Th2 cells through activation of the phosphatidylinositol 3-kinase pathway.

Ítems similars

• Inhibition of PI3K and calcineurin suppresses chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)-dependent responses of Th2 lymphocytes to prostaglandin D(2).
  per: Xue, L, et al.
  Publicat: (2007)
• A dominant role for chemoattractant receptor-homologous molecule expressed on T helper type 2 (Th2) cells (CRTH2) in mediating chemotaxis of CRTH2+ CD4+ Th2 lymphocytes in response to mast cell supernatants.
  per: Gyles, S, et al.
  Publicat: (2006)
• Delta12-prostaglandin D2 is a potent and selective CRTH2 receptor agonist and causes activation of human eosinophils and Th2 lymphocytes.
  per: Gazi, L, et al.
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• CRTH2 mediates the activation of human Th2 cells in response to PGD(2) released from IgE/anti-IgE treated nasal polyp tissue.
  per: Pérez-Novo, C, et al.
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• Indole-3-acetic acid antagonists of the prostaglandin D2 receptor CRTH2.
  per: Armer, R, et al.
  Publicat: (2005)