Regulation of pain sensitivity in experimental osteoarthritis by the endogenous peripheral opioid system.

OBJECTIVE: OA is the most common joint disease, affecting 10-15% of people over 60 years of age. However, up to 40% of individuals with radiologic damage are asymptomatic. The purpose of this study was to assess the role of the endogenous opioid system in delaying the onset of pain in a murine mode...

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Bibliographic Details
Main Authors: Inglis, J, McNamee, K, Chia, S, Essex, D, Feldmann, M, Williams, R, Hunt, S, Vincent, T
Format: Journal article
Language:English
Published: 2008