Safety and High Level Efficacy of the Combination Malaria Vaccine Regimen of RTS,S/AS01B With Chimpanzee Adenovirus 63 and Modified Vaccinia Ankara Vectored Vaccines Expressing ME-TRAP

Safety and High Level Efficacy of the Combination Malaria Vaccine Regimen of RTS,S/AS01B With Chimpanzee Adenovirus 63 and Modified Vaccinia Ankara Vectored Vaccines Expressing ME-TRAP

The need for a highly efficacious vaccine against Plasmodium falciparum remains pressing. In this controlled human malaria infection (CHMI) study, we assessed the safety, efficacy and immunogenicity of a schedule combining 2 distinct vaccine types in a staggered immunization regimen: one inducing hi...

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Những tác giả chính: Rampling, T, Ewer, KJ, Bowyer, G, Bliss, CM, Edwards, NJ, Wright, D, Payne, RO, Venkatraman, N, de Barra, E, Snudden, CM, Poulton, ID, de Graaf, H, Sukhtankar, P, Roberts, R, Ivinson, K, Weltzin, R, Rajkumar, BY, Wille-Reece, U, Lee, CK, Ockenhouse, CF, Sinden, RE, Gerry, S, Lawrie, AM, Vekemans, J, Morelle, D, Lievens, M, Ballou, RW, Cooke, GS, Faust, SN, Gilbert, S, Hill, AV
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Oxford University Press 2016

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