The structure and biochemical properties of the human spliceosomal protein U1C.

The spliceosomal U1C protein is critical to the initiation and regulation of precursor messenger RNA (pre-mRNA) splicing, as part of the U1 small nuclear ribonucleoprotein particle (snRNP). We have produced full-length and 61 residue constructs of human U1C in soluble form in Escherichia coli. Atomi...

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Bibliographic Details
Main Authors: Muto, Y, Pomeranz Krummel, D, Oubridge, C, Hernandez, H, Robinson, C, Neuhaus, D, Nagai, K
Format: Journal article
Language:English
Published: 2004