Basic FGF mediates an immediate response of articular cartilage to mechanical injury.

The extracellularly regulated kinase (ERK), one of the three types of mitogen-activated kinases, was rapidly activated after cutting porcine articular cartilage either when maintained as explants or in situ. Cutting released a soluble ERK-activating factor from the cartilage, which was purified and...

Full description

Bibliographic Details
Main Authors: Vincent, T, Hermansson, M, Bolton, M, Wait, R, Saklatvala, J
Format: Journal article
Language:English
Published: 2002