Basic FGF mediates an immediate response of articular cartilage to mechanical injury.

The extracellularly regulated kinase (ERK), one of the three types of mitogen-activated kinases, was rapidly activated after cutting porcine articular cartilage either when maintained as explants or in situ. Cutting released a soluble ERK-activating factor from the cartilage, which was purified and...

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Détails bibliographiques
Auteurs principaux: Vincent, T, Hermansson, M, Bolton, M, Wait, R, Saklatvala, J
Format: Journal article
Langue:English
Publié: 2002

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