Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

Body-fat distribution is a risk factor for adverse cardiovascular health consequences. We analyzed the association of body-fat distribution, assessed by waist-to-hip ratio adjusted for body mass index, with 228,985 predicted coding and splice site variants available on exome arrays in up to 344,369...

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Main Authors: Justice, A, Karaderi, T, Highland, H, Mahajan, A, Gan, W, Karpe, F, Kitajima, H, McCarthy, M, Morris, A, Neville, C, Owen, K, Robertson, N, Southam, L, Lindgren, C
格式: Journal article
出版: Nature Publishing Group 2019