Mechanisms of oocyte activation in the presence and absence of PLCζ
Mammalian oocyte activation is thought to be caused by a sperm borne PLC subtype, called phospholipase C zeta1 (PLCζ). PLCζ RNA and protein microinjection and knockout studies in a mouse model have confirmed its primary role in releasing calcium (Ca2+) in the oocyte at fertilisation. Studies reveale...
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| Format: | Thesis |
| Language: | English |
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2020
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