Large-scale analysis of the relationship between CYP11A promoter variation, polycystic ovarian syndrome, and serum testosterone.

CYP11A, the gene encoding p450scc, a key enzyme in steroid biosynthesis, is a strong biological candidate for polycystic ovary syndrome (PCOS) susceptibility. Four of the five published studies that have examined CYP11A for evidence of linkage and/or association have reported significant relationshi...

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Bibliographic Details
Main Authors: Gaasenbeek, M, Powell, B, Sovio, U, Haddad, L, Gharani, N, Bennett, A, Groves, C, Rush, K, Goh, M, Conway, G, Ruokonen, A, Martikainen, H, Pouta, A, Taponen, S, Hartikainen, A, Halford, S, Järvelin, MR, Franks, S, McCarthy, M
Format: Journal article
Language:English
Published: 2004