Insights about clonal hematopoiesis from 8,342 mosaic chromosomal alterations
The selective pressures that shape clonal evolution in healthy individuals are largely unknown. Here we investigate 8,342 mosaic chromosomal alterations (mCAs) of length 50kb–249Mb that we uncovered in blood-derived DNA from 151,202 UK Biobank participants using new phase-based computational techniq...
| Main Authors: | , , , , , , , , , , |
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| Format: | Journal article |
| Published: |
Nature Publishing Group
2018
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