A new modular approach to nanoassembly: stable and addressable DNA nanoconstructs via orthogonal click chemistries.
Thermodynamic instability is a problem when assembling and purifying complex DNA nanostructures formed by hybridization alone. To address this issue, we have used photochemical fixation and orthogonal copper-free, ring-strain-promoted, click chemistry for the synthesis of dimeric, trimeric, and olig...
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2012
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