A new modular approach to nanoassembly: stable and addressable DNA nanoconstructs via orthogonal click chemistries.

Thermodynamic instability is a problem when assembling and purifying complex DNA nanostructures formed by hybridization alone. To address this issue, we have used photochemical fixation and orthogonal copper-free, ring-strain-promoted, click chemistry for the synthesis of dimeric, trimeric, and olig...

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Bibliographic Details
Main Authors: Gerrard, SR, Hardiman, C, Shelbourne, M, Nandhakumar, I, Nordén, B, Brown, T
Format: Journal article
Language:English
Published: 2012