Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy.

Previous attempts to identify neuroprotective targets by studying the ischemic cascade and devising ways to suppress it have failed to translate to efficacious therapies for acute ischemic stroke. We hypothesized that studying the molecular determinants of endogenous neuroprotection in two well-esta...

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Bibliographic Details
Main Authors: Papadakis, M, Hadley, G, Xilouri, M, Hoyte, L, Nagel, S, McMenamin, M, Tsaknakis, G, Watt, S, Drakesmith, C, Chen, R, Wood, M, Zhao, Z, Kessler, B, Vekrellis, K, Buchan, A
Format: Journal article
Language:English
Published: Nature Publishing Group 2013