The role of extra-membranous inter-helical loops in helix-helix interactions.

The effect of a short loop connecting two transmembrane alpha-helices was studied using molecular dynamics simulations. Helices F and G from bacteriorhodopsin and two corresponding polyalanine helices were embedded in octane and POPC membranes in a transmembrane configuration both with and without t...

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Bibliographic Details
Main Authors: Ulmschneider, M, Tieleman, D, Sansom, MS
Format: Journal article
Language:English
Published: 2005