PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation.
Posttranslational modification of chromatin by histone methylation has wide-ranging effects on nuclear function, including transcriptional regulation, maintenance of genome integrity, and epigenetic inheritance. The enzymes utilized to place histone methylation marks are well characterized, but the...
প্রধান লেখক: | , , , , , , , , |
---|---|
বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
2007
|