PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation.

PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation.

Posttranslational modification of chromatin by histone methylation has wide-ranging effects on nuclear function, including transcriptional regulation, maintenance of genome integrity, and epigenetic inheritance. The enzymes utilized to place histone methylation marks are well characterized, but the...

Podrobná bibliografie
Hlavní autoři:	Yamane, K, Tateishi, K, Klose, R, Fang, J, Fabrizio, L, Erdjument-Bromage, H, Taylor-Papadimitriou, J, Tempst, P, Zhang, Y
Médium:	Journal article
Jazyk:	English
Vydáno:	2007

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