PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation.
Posttranslational modification of chromatin by histone methylation has wide-ranging effects on nuclear function, including transcriptional regulation, maintenance of genome integrity, and epigenetic inheritance. The enzymes utilized to place histone methylation marks are well characterized, but the...
Main Authors: | Yamane, K, Tateishi, K, Klose, R, Fang, J, Fabrizio, L, Erdjument-Bromage, H, Taylor-Papadimitriou, J, Tempst, P, Zhang, Y |
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Format: | Journal article |
Language: | English |
Published: |
2007
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