Characterising cancer cell responses to cyclic hypoxia using mathematical modelling
In vivo observations show that oxygen levels in tumours can fluctuate on fast and slow timescales. As a result, cancer cells can be periodically exposed to pathologically low oxygen levels; a phenomenon known as cyclic hypoxia. Yet, little is known about the response and adaptation of cancer cells t...
Main Authors: | Celora, GL, Nixson, R, Pitt-Francis, J, Maini, P, Byrne, H |
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格式: | Journal article |
語言: | English |
出版: |
Springer
2024
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