The enzymology of clavam and carbapenem biosynthesis.

The enzyme-catalysed reactions involved in formation of the bicyclic clavam and carbapenem nuclei, including beta-amino acid and beta-lactam formation, are discussed and compared with those involved in penicillin and cephalosporin biosynthesis. The common role of unusual oxidation reactions in the b...

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Autors principals: Kershaw, N, Caines, M, Sleeman, M, Schofield, C
Format: Journal article
Idioma:English
Publicat: 2005