The role of the DNA sliding clamp in Okazaki fragment maturation in archaea and eukaryotes.
Efficient processing of Okazaki fragments generated during discontinuous lagging-strand DNA replication is critical for the maintenance of genome integrity. In eukaryotes, a number of enzymes co-ordinate to ensure the removal of initiating primers from the 5'-end of each fragment and the genera...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2011
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