Review: Modulation of striatal neuron activity by cyclic nucleotide signaling and phosphodiesterase inhibition.

The cyclic nucleotides cAMP and cGMP are common signaling molecules synthesized in neurons following the activation of adenylyl or guanylyl cyclase. In the striatum, the synthesis and degradation of cAMP and cGMP is highly regulated as these second messengers have potent effects on the activity of s...

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Bibliographic Details
Main Authors: Threlfell, S, West, A
Format: Journal article
Language:English
Published: Elsevier 2013