Thymosin β4 protects against aortic aneurysm via endocytic regulation of growth factor signaling

Vascular stability and tone are maintained by contractile smooth muscle cells (VSMCs). However, injury-induced growth factors stimulate a contractile-synthetic phenotypic modulation which increases susceptibility to abdominal aortic aneurysm (AAA). As a regulator of embryonic VSMC differentiation, w...

Description complète

Détails bibliographiques
Auteurs principaux: Munshaw, S, Bruche, S, Redpath, A, Jones, A, Patel, J, Dube, K, Lee, R, Hester, S, Davies, R, Neal, G, Handa, A, Sattler, M, Fischer, R, Channon, K, Smart, N
Format: Journal article
Langue:English
Publié: American Society for Clinical Investigation 2021