Expanding the malaria antibody toolkit: development and characterisation of Plasmodium falciparum RH5, CyRPA, and CSP recombinant human monoclonal antibodies

Expanding the malaria antibody toolkit: development and characterisation of Plasmodium falciparum RH5, CyRPA, and CSP recombinant human monoclonal antibodies

Malaria, an infection caused by apicomplexan parasites of the genus Plasmodium, continues to exact a significant toll on public health with over 200 million cases world-wide, and annual deaths in excess of 600,000. Considerable progress has been made to reduce malaria burden in endemic countries in...

書誌詳細
主要な著者:	Nacer, A, Kivi, G, Pert, R, Juronen, E, Holenya, P, Aliprandini, E, Amino, R, Silvie, O, Quinkert, D, Le Duff, Y, Hurley, M, Reimer, U, Tover, A, Draper, SJ, Gilbert, S, Ho, MM, Bowyer, PW
フォーマット:	Journal article
言語:	English
出版事項:	Frontiers Media 2022

類似資料

Expanding the Malaria Antibody Toolkit: Development and Characterisation of Plasmodium falciparum RH5, CyRPA, and CSP Recombinant Human Monoclonal Antibodies
著者:: Adéla Nacer, 等
出版事項: (2022-06-01)

Structural basis for inhibition of erythrocyte invasion by antibodies to Plasmodium falciparum protein CyRPA
著者:: Lin Chen, 等
出版事項: (2017-02-01)

The RH5-CyRPA-Ripr complex as a malaria vaccine target
著者:: Ragotte, RJ, 等
出版事項: (2020)

Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody
著者:: Paola Favuzza, 等
出版事項: (2017-02-01)

Divergent roles for the RH5 complex components, CyRPA and RIPR in human-infective malaria parasites
著者:: Knuepfer, E, 等
出版事項: (2019)

Divergent roles for the RH5 complex components, CyRPA and RIPR in human-infective malaria parasites.
著者:: Ellen Knuepfer, 等
出版事項: (2019-06-01)

Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex
著者:: Williams, BG, 等
出版事項: (2024)

Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex
著者:: Barnabas G. Williams, 等
出版事項: (2024-06-01)

Bliss' and Loewe's additive and synergistic effects in Plasmodium falciparum growth inhibition by AMA1-RON2L, RH5, RIPR and CyRPA antibody combinations
著者:: Azasi, Y, 等
出版事項: (2020)

Cysteine-Rich Protective Antigen (CyRPA) as promising blood-stage candidate protein for inclusion in a malaria subunit vaccine
著者:: Favuzza Paola, 等
出版事項: (2012-10-01)

RH5.1-CyRPA-Ripr antigen combination vaccine shows little improvement over RH5.1 in a preclinical setting
著者:: Healer, J, 等
出版事項: (2022)

RH5.1-CyRPA-Ripr antigen combination vaccine shows little improvement over RH5.1 in a preclinical setting
著者:: Julie Healer, 等
出版事項: (2022-12-01)

Process development and preclinical evaluation of a major Plasmodium falciparum blood stage vaccine candidate, Cysteine-Rich Protective Antigen (CyRPA)
著者:: Anjali Somanathan, 等
出版事項: (2022-09-01)

The dual action of human antibodies specific to Plasmodium falciparum PfRH5 and PfCyRPA: Blocking invasion and inactivating extracellular merozoites
著者:: Weiss, GE, 等
出版事項: (2023)

The dual action of human antibodies specific to Plasmodium falciparum PfRH5 and PfCyRPA: Blocking invasion and inactivating extracellular merozoites.
著者:: Greta E Weiss, 等
出版事項: (2023-09-01)

Dynamics of IgM and IgG Antibody Response Profile against Linear B-Cell Epitopes from Exoerythrocytic (CelTOS and TRAP) and Erythrocytic (CyRPA) Phases of <i>Plasmodium vivax</i>: Follow-Up Study
著者:: Cinthia Magalhães Rodolphi, 等
出版事項: (2024-08-01)

The molecular basis of Plasmodium falciparum merozoite invasion inhibition via anti-PfCyRPA antibodies
著者:: Ragotte, R
出版事項: (2020)

Low antibody titers against malaria vaccine candidates RH5, RIPR and CYRPA in naturally infected people in an endemic area of Mali
著者:: Draper, S, 等
出版事項: (2018)

Signal stability of Cy3 and Cy5 on antibody microarrays
著者:: Kim Caroline, 等
出版事項: (2006-10-01)

Leveraging Immunofocusing and Virus-like Particle Display to Enhance Antibody Responses to the Malaria Blood-Stage Invasion Complex Antigen PfCyRPA
著者:: Kasper H. Björnsson, 等
出版事項: (2024-07-01)

The essential malaria protein PfCyRPA targets glycans to invade erythrocytes
著者:: Christopher J. Day, 等
出版事項: (2024-04-01)

Heterotypic interactions drive antibody synergy against a malaria vaccine candidate
著者:: Ragotte, RJ, 等
出版事項: (2022)

The malaria blood stage antigen PfCyRPA formulated with the TLR-4 agonist adjuvant GLA-SE elicits parasite growth inhibitory antibodies in experimental animals
著者:: Marco Tamborrini, 等
出版事項: (2023-07-01)

Sporozoite motility as a quantitative readout for anti-CSP antibody inhibition
著者:: C. M. de Korne, 等
出版事項: (2022-10-01)

Cytotoxicity of human antibodies targeting the circumsporozoite protein is amplified by 3D substrate and correlates with protection
著者:: Manuela C. Aguirre-Botero, 等
出版事項: (2023-07-01)

A Multistage Formulation Based on Full-Length CSP and AMA-1 Ectodomain of <i>Plasmodium vivax</i> Induces High Antibody Titers and T-cells and Partially Protects Mice Challenged with a Transgenic <i>Plasmodium berghei</i> Parasite
著者:: Luciana C. Lima, 等
出版事項: (2020-06-01)

Characterization of T and B cell epitopes in PvCyRPA by studying the naturally acquired immune response in Brazilian Amazon communities
著者:: Isabela Ferreira Soares, 等
出版事項: (2024-11-01)

Using Cy5-dUTP labelling of RPA-amplicons with downstream microarray analysis for the detection of antibiotic resistance genes
著者:: Christian Warmt, 等
出版事項: (2021-10-01)

Late killing of Plasmodium berghei sporozoites in the liver by an anti-circumsporozoite protein antibody
著者:: Manuela C Aguirre-Botero, 等
出版事項: (2025-02-01)

Molecular and functional properties of human Plasmodium falciparum CSP C‐terminus antibodies
著者:: Opeyemi Ernest Oludada, 等
出版事項: (2023-04-01)

Immunogenicity of PvCyRPA, PvCelTOS and Pvs25 chimeric recombinant protein of Plasmodium vivax in murine model
著者:: Matos, ADS, 等
出版事項: (2024)

Immunogenicity of PvCyRPA, PvCelTOS and Pvs25 chimeric recombinant protein of Plasmodium vivax in murine model
著者:: Ada da Silva Matos, 等
出版事項: (2024-06-01)

Adeno‐associated viral vectored delivery of a monoclonal antibody gene against blood‐stage malaria
著者:: Bardelli, M, 等
出版事項: (2019)

Anti-TRAP/SSP2 monoclonal antibodies can inhibit sporozoite infection and may enhance protection of anti-CSP monoclonal antibodies
著者:: Brandon K. Wilder, 等
出版事項: (2022-05-01)

Heterotypic interactions drive antibody synergy against a malaria vaccine candidate
著者:: Robert J. Ragotte, 等
出版事項: (2022-02-01)

Scalable Process for High-Yield Production of PfCyRPA Using Insect Cells for Inclusion in a Malaria Virosome-Based Vaccine Candidate
著者:: Bárbara Fernandes, 等
出版事項: (2022-05-01)

Seven-year kinetics of RTS, S/AS01-induced anti-CSP antibodies in young Kenyan children
著者:: Mugo, RM, 等
出版事項: (2021)

Seven-year kinetics of RTS, S/AS01-induced anti-CSP antibodies in young Kenyan children
著者:: Robert M. Mugo, 等
出版事項: (2021-12-01)

Adeno-associated viral vectored delivery of a novel monoclonal antibody gene against blood-stage Plasmodium falciparum malaria
著者:: Bardelli, M, 等
出版事項: (2018)

Microarray: Working with Cy3 and Cy5
著者:: Kristie Nybo
出版事項: (2013-09-01)