Haemolysis in G6PD heterozygous females treated with primaquine for Plasmodium vivax malaria: a nested cohort in a trial of radical curative regimens

BACKGROUND: Radical cure of Plasmodium vivax malaria with 8-aminoquinolines (primaquine or tafenoquine) is complicated by haemolysis in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. G6PD heterozygous females, because of individual variation in the pattern of X-chromosome inac...

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Main Authors: Chu, C, Bancone, G, Moore, K, Win, H, Thitipanawan, N, Po, C, Chowwiwat, N, Raksapraidee, R, Wilairisak, P, Phyo, A, Keereecharoen, L, Proux, S, Charunwatthana, P, Nosten, F, White, N
Format: Journal article
Language:English
Published: Public Library of Science 2017