RORγt inhibitors suppress TH17 responses in inflammatory arthritis and inflammatory bowel disease.

Increased frequencies of T-helper cells producing the proinflammatory cytokine IL-17A (TH17) have been reported in ankylosing spondylitis (AS), rheumatoid arthritis (RA), psoriatic arthritis (PsA), and inflammatory bowel disease (IBD).1 Genome-wide association studies have linked multiple TH17-assoc...

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Bibliographic Details
Main Authors:	de Wit, J, Al-Mossawi, M, Hühn, M, Arancibia-Cárcamo, C, Doig, K, Kendrick, B, Gundle, R, Taylor, P, Mcclanahan, T, Murphy, E, Zhang, H, Barr, K, Miller, J, Hu, X, Aicher, T, Morgan, R, Glick, G, Zaller, D, Correll, C, Powrie, F, Bowness, P
Format:	Journal article
Language:	English
Published:	Elsevier 2015

RORγt inhibitors suppress TH17 responses in inflammatory arthritis and inflammatory bowel disease.

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