Analysis of a T-cell receptor V beta segment implicated in susceptibility to rheumatoid arthritis: V beta 2 germline polymorphism does not encode susceptibility.

OBJECTIVES: The assessment of allelic polymorphism of the T cell receptor gene segment, TCRBV2S1, in rheumatoid arthritis. METHODS: A total of 136 patients with rheumatoid arthritis (RA) (ACR criteria) and 150 controls were TCRBV2S1 genotyped using a nested PCR amplification strategy followed by sin...

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Bibliographic Details
Main Authors: Pile, K, Wordsworth, P, Lioté, F, Bardin, T, Bell, J, Cornélis, F
Format: Journal article
Language:English
Published: 1993