RNA polymerase pausing during initial transcription

RNA polymerase pausing during initial transcription

In bacteria, RNA polymerase (RNAP) initiates transcription by synthesizing short transcripts that are either released or extended to allow RNAP to escape from the promoter. The mechanism of initial transcription is unclear due to the presence of transient intermediates and molecular heterogeneity. H...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Duchi, D, Bauer, D, Fernandez, L, Evans, G, Robb, N, Hwang, L, Gryte, K, Tomescu, A, Zawadzki, P, Morichaud, Z, Brodolin, K, Kapanidis, A
التنسيق:	Journal article
اللغة:	English
منشور في:	Cell Press 2016

مواد مشابهة

Conformational heterogeneity and bubble dynamics in single bacterial transcription initiation complexes
حسب: Duchi, D, وآخرون
منشور في: (2017)

Pausing controls branching between productive and non-productive pathways during initial transcription in bacteria
حسب: Dulin, D, وآخرون
منشور في: (2018)

The transcription bubble of the RNA polymerase-promoter open complex exhibits conformational heterogeneity and millisecond-scale dynamics: Implications for transcription start-site selection
حسب: Robb, N, وآخرون
منشور في: (2013)

The transcription bubble of the RNA polymerase-promoter open complex exhibits conformational heterogeneity and millisecond-scale dynamics: implications for transcription start-site selection.
حسب: Robb, N, وآخرون
منشور في: (2013)

Pausing controls branching between productive and non-productive pathways during initial transcription in bacteria
حسب: David Dulin, وآخرون
منشور في: (2018-04-01)

Single-Molecule Studies of Transcription Initiation using a Vesicle Approach
حسب: Llumigusin, D, وآخرون
منشور في: (2012)

CDK9-dependent RNA polymerase II pausing controls transcription initiation
حسب: Saskia Gressel, وآخرون
منشور في: (2017-10-01)

Real-time transcription initiation by E. coli RNA polymerase in vitro and in vivo
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منشور في: (2015)

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حسب: Abderhman Abuhashem, وآخرون
منشور في: (2022-01-01)

Sensing DNA opening in transcription using quenchable Forster resonance energy transfer.
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منشور في: (2010)

A pause site for RNA polymerase II is associated with termination of transcription.
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Role of R-loops in pause-dependent transcriptional termination of RNA polymerase II
حسب: Skourti-Stathaki, K
منشور في: (2012)

Pause sequences facilitate entry into long-lived paused states by reducing RNA polymerase transcription rates
حسب: Ronen Gabizon, وآخرون
منشور في: (2018-07-01)

Pause sites promote transcriptional termination of mammalian RNA polymerase II.
حسب: Gromak, N, وآخرون
منشور في: (2006)

Role of RNA Polymerase II Promoter-Proximal Pausing in Viral Transcription
حسب: Marilyn Whelan, وآخرون
منشور في: (2022-09-01)

Characterizing Influenza a RNA Polymerase - Promoter Interaction using Ensemble Fluorescence Spectroscopy
حسب: Tomescu, A, وآخرون
منشور في: (2013)

Single-molecule FRET reveals a corkscrew RNA structure for the polymerase-bound influenza virus promoter.
حسب: Tomescu, A, وآخرون
منشور في: (2014)

Initial transcription by RNA polymerase proceeds through a DNA-scrunching mechanism.
حسب: Kapanidis, A, وآخرون
منشور في: (2006)

Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization
حسب: Zakia Morichaud, وآخرون
منشور في: (2023-01-01)

Single-molecule studies of transcription initiation
حسب: Duchi Llumigusin, D, وآخرون
منشور في: (2014)

The RNA polymerase clamp interconverts dynamically among three states and is stabilized in a partly closed state by ppGpp
حسب: Duchi, D, وآخرون
منشور في: (2018)

A Role for FACT in RNA Polymerase II Promoter-Proximal Pausing
حسب: Theophilus T. Tettey, وآخرون
منشور في: (2019-06-01)

A-MYB and BRDT-dependent RNA Polymerase II pause release orchestrates transcriptional regulation in mammalian meiosis
حسب: Adriana K. Alexander, وآخرون
منشور في: (2023-03-01)

The pause-initiation limit restricts transcription activation in human cells
حسب: Saskia Gressel, وآخرون
منشور في: (2019-08-01)

Reporter-ChIP-nexus reveals strong contribution of the Drosophila initiator sequence to RNA polymerase pausing
حسب: Wanqing Shao, وآخرون
منشور في: (2019-04-01)

The elemental mechanism of transcriptional pausing
حسب: Jason Saba, وآخرون
منشور في: (2019-01-01)

Poly(A) signals and transcriptional pause sites combine to prevent interference between RNA polymerase II promoters.
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RNA polymerase II pausing downstream of core histone genes is different from genes producing polyadenylated transcripts.
حسب: Krishanpal Anamika, وآخرون
منشور في: (2012-01-01)

Improved temporal resolution and linked hidden Markov modeling for switchable single-molecule FRET.
حسب: Uphoff, S, وآخرون
منشور في: (2011)

Transcription Pause and Escape in Neurodevelopmental Disorders
حسب: Kristel N. Eigenhuis, وآخرون
منشور في: (2022-05-01)

Tyrosine 1-phosphorylated RNA polymerase II transcribes PROMPTs to facilitate proximal promoter pausing and induce global transcriptional repression in response to DNA damage
حسب: Ajit, K, وآخرون
منشور في: (2024)

New core promoter element in RNA polymerase II-dependent transcription: sequence-specific DNA binding by transcription factor IIB.
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Transcriptional regulation: effects of promoter proximal pausing on speed, synchrony and reliability.
حسب: Alistair N Boettiger, وآخرون
منشور في: (2011-05-01)

RNA Polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation
حسب: Martell, DJ, وآخرون
منشور في: (2023)

RNA polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation.
حسب: Martell, DJ, وآخرون
منشور في: (2023)

Grounded: Transcriptional Pausing in Naive mESCs
حسب: Guenther, Matthew G., وآخرون
منشور في: (2014)

YEAST RNA POLYMERASE-II TRANSCRIPTION - ENZYMATIC-ACTIVITIES OF GENERAL INITIATION-FACTORS, 3-D STRUCTURES OF INITIATION-FACTORS AND RNA-POLYMERASE, AND MECHANISM OF TRANSCRIPTIONAL ACTIVATION
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Structures of co-transcriptional RNA capping enzymes on paused transcription complex
حسب: Yan Li, وآخرون
منشور في: (2024-05-01)

Definition of transcriptional pause elements in fission yeast.
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منشور في: (1999)

c-Myc regulates transcriptional pause release
حسب: Rahl, Peter B., وآخرون
منشور في: (2012)