RNA polymerase pausing during initial transcription

RNA polymerase pausing during initial transcription

In bacteria, RNA polymerase (RNAP) initiates transcription by synthesizing short transcripts that are either released or extended to allow RNAP to escape from the promoter. The mechanism of initial transcription is unclear due to the presence of transient intermediates and molecular heterogeneity. H...

書誌詳細
主要な著者:	Duchi, D, Bauer, D, Fernandez, L, Evans, G, Robb, N, Hwang, L, Gryte, K, Tomescu, A, Zawadzki, P, Morichaud, Z, Brodolin, K, Kapanidis, A
フォーマット:	Journal article
言語:	English
出版事項:	Cell Press 2016

類似資料

Conformational heterogeneity and bubble dynamics in single bacterial transcription initiation complexes
著者:: Duchi, D, 等
出版事項: (2017)

Pausing controls branching between productive and non-productive pathways during initial transcription in bacteria
著者:: Dulin, D, 等
出版事項: (2018)

The transcription bubble of the RNA polymerase-promoter open complex exhibits conformational heterogeneity and millisecond-scale dynamics: Implications for transcription start-site selection
著者:: Robb, N, 等
出版事項: (2013)

The transcription bubble of the RNA polymerase-promoter open complex exhibits conformational heterogeneity and millisecond-scale dynamics: implications for transcription start-site selection.
著者:: Robb, N, 等
出版事項: (2013)

Pausing controls branching between productive and non-productive pathways during initial transcription in bacteria
著者:: David Dulin, 等
出版事項: (2018-04-01)

Single-Molecule Studies of Transcription Initiation using a Vesicle Approach
著者:: Llumigusin, D, 等
出版事項: (2012)

CDK9-dependent RNA polymerase II pausing controls transcription initiation
著者:: Saskia Gressel, 等
出版事項: (2017-10-01)

Real-time transcription initiation by E. coli RNA polymerase in vitro and in vivo
著者:: Plochowietz, A, 等
出版事項: (2015)

RNA polymerase II pausing in development: orchestrating transcription
著者:: Abderhman Abuhashem, 等
出版事項: (2022-01-01)

Sensing DNA opening in transcription using quenchable Forster resonance energy transfer.
著者:: Cordes, T, 等
出版事項: (2010)

A pause site for RNA polymerase II is associated with termination of transcription.
著者:: Enriquez-Harris, P, 等
出版事項: (1991)

Role of R-loops in pause-dependent transcriptional termination of RNA polymerase II
著者:: Skourti-Stathaki, K
出版事項: (2012)

Pause sequences facilitate entry into long-lived paused states by reducing RNA polymerase transcription rates
著者:: Ronen Gabizon, 等
出版事項: (2018-07-01)

Pause sites promote transcriptional termination of mammalian RNA polymerase II.
著者:: Gromak, N, 等
出版事項: (2006)

Role of RNA Polymerase II Promoter-Proximal Pausing in Viral Transcription
著者:: Marilyn Whelan, 等
出版事項: (2022-09-01)

Characterizing Influenza a RNA Polymerase - Promoter Interaction using Ensemble Fluorescence Spectroscopy
著者:: Tomescu, A, 等
出版事項: (2013)

Single-molecule FRET reveals a corkscrew RNA structure for the polymerase-bound influenza virus promoter.
著者:: Tomescu, A, 等
出版事項: (2014)

Initial transcription by RNA polymerase proceeds through a DNA-scrunching mechanism.
著者:: Kapanidis, A, 等
出版事項: (2006)

Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization
著者:: Zakia Morichaud, 等
出版事項: (2023-01-01)

Single-molecule studies of transcription initiation
著者:: Duchi Llumigusin, D, 等
出版事項: (2014)

The RNA polymerase clamp interconverts dynamically among three states and is stabilized in a partly closed state by ppGpp
著者:: Duchi, D, 等
出版事項: (2018)

A Role for FACT in RNA Polymerase II Promoter-Proximal Pausing
著者:: Theophilus T. Tettey, 等
出版事項: (2019-06-01)

A-MYB and BRDT-dependent RNA Polymerase II pause release orchestrates transcriptional regulation in mammalian meiosis
著者:: Adriana K. Alexander, 等
出版事項: (2023-03-01)

The pause-initiation limit restricts transcription activation in human cells
著者:: Saskia Gressel, 等
出版事項: (2019-08-01)

Reporter-ChIP-nexus reveals strong contribution of the Drosophila initiator sequence to RNA polymerase pausing
著者:: Wanqing Shao, 等
出版事項: (2019-04-01)

The elemental mechanism of transcriptional pausing
著者:: Jason Saba, 等
出版事項: (2019-01-01)

Poly(A) signals and transcriptional pause sites combine to prevent interference between RNA polymerase II promoters.
著者:: Eggermont, J, 等
出版事項: (1993)

RNA polymerase II pausing downstream of core histone genes is different from genes producing polyadenylated transcripts.
著者:: Krishanpal Anamika, 等
出版事項: (2012-01-01)

Improved temporal resolution and linked hidden Markov modeling for switchable single-molecule FRET.
著者:: Uphoff, S, 等
出版事項: (2011)

Transcription Pause and Escape in Neurodevelopmental Disorders
著者:: Kristel N. Eigenhuis, 等
出版事項: (2022-05-01)

Tyrosine 1-phosphorylated RNA polymerase II transcribes PROMPTs to facilitate proximal promoter pausing and induce global transcriptional repression in response to DNA damage
著者:: Ajit, K, 等
出版事項: (2024)

New core promoter element in RNA polymerase II-dependent transcription: sequence-specific DNA binding by transcription factor IIB.
著者:: Lagrange, T, 等
出版事項: (1998)

Transcriptional regulation: effects of promoter proximal pausing on speed, synchrony and reliability.
著者:: Alistair N Boettiger, 等
出版事項: (2011-05-01)

RNA Polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation
著者:: Martell, DJ, 等
出版事項: (2023)

RNA polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation.
著者:: Martell, DJ, 等
出版事項: (2023)

Grounded: Transcriptional Pausing in Naive mESCs
著者:: Guenther, Matthew G., 等
出版事項: (2014)

YEAST RNA POLYMERASE-II TRANSCRIPTION - ENZYMATIC-ACTIVITIES OF GENERAL INITIATION-FACTORS, 3-D STRUCTURES OF INITIATION-FACTORS AND RNA-POLYMERASE, AND MECHANISM OF TRANSCRIPTIONAL ACTIVATION
著者:: Kornberg, R, 等
出版事項: (1992)

Structures of co-transcriptional RNA capping enzymes on paused transcription complex
著者:: Yan Li, 等
出版事項: (2024-05-01)

Definition of transcriptional pause elements in fission yeast.
著者:: Aranda, A, 等
出版事項: (1999)

c-Myc regulates transcriptional pause release
著者:: Rahl, Peter B., 等
出版事項: (2012)