RNA polymerase pausing during initial transcription

RNA polymerase pausing during initial transcription

In bacteria, RNA polymerase (RNAP) initiates transcription by synthesizing short transcripts that are either released or extended to allow RNAP to escape from the promoter. The mechanism of initial transcription is unclear due to the presence of transient intermediates and molecular heterogeneity. H...

Bibliográfalaš dieđut
Váldodahkkit:	Duchi, D, Bauer, D, Fernandez, L, Evans, G, Robb, N, Hwang, L, Gryte, K, Tomescu, A, Zawadzki, P, Morichaud, Z, Brodolin, K, Kapanidis, A
Materiálatiipa:	Journal article
Giella:	English
Almmustuhtton:	Cell Press 2016

Geahča maid

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Almmustuhtton: (2017)

Pausing controls branching between productive and non-productive pathways during initial transcription in bacteria
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Almmustuhtton: (2018)

The transcription bubble of the RNA polymerase-promoter open complex exhibits conformational heterogeneity and millisecond-scale dynamics: Implications for transcription start-site selection
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Almmustuhtton: (2013)

The transcription bubble of the RNA polymerase-promoter open complex exhibits conformational heterogeneity and millisecond-scale dynamics: implications for transcription start-site selection.
Dahkki: Robb, N, et al.
Almmustuhtton: (2013)

Pausing controls branching between productive and non-productive pathways during initial transcription in bacteria
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Almmustuhtton: (2018-04-01)

Single-Molecule Studies of Transcription Initiation using a Vesicle Approach
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Almmustuhtton: (2012)

CDK9-dependent RNA polymerase II pausing controls transcription initiation
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Almmustuhtton: (2017-10-01)

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RNA polymerase II pausing in development: orchestrating transcription
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Almmustuhtton: (2022-01-01)

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Almmustuhtton: (2010)

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Almmustuhtton: (2012)

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Almmustuhtton: (2018-07-01)

Pause sites promote transcriptional termination of mammalian RNA polymerase II.
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Role of RNA Polymerase II Promoter-Proximal Pausing in Viral Transcription
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Almmustuhtton: (2022-09-01)

Characterizing Influenza a RNA Polymerase - Promoter Interaction using Ensemble Fluorescence Spectroscopy
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Single-molecule FRET reveals a corkscrew RNA structure for the polymerase-bound influenza virus promoter.
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Initial transcription by RNA polymerase proceeds through a DNA-scrunching mechanism.
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Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization
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Almmustuhtton: (2023-01-01)

Single-molecule studies of transcription initiation
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Almmustuhtton: (2014)

The RNA polymerase clamp interconverts dynamically among three states and is stabilized in a partly closed state by ppGpp
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Almmustuhtton: (2018)

A Role for FACT in RNA Polymerase II Promoter-Proximal Pausing
Dahkki: Theophilus T. Tettey, et al.
Almmustuhtton: (2019-06-01)

A-MYB and BRDT-dependent RNA Polymerase II pause release orchestrates transcriptional regulation in mammalian meiosis
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Almmustuhtton: (2023-03-01)

The pause-initiation limit restricts transcription activation in human cells
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Almmustuhtton: (2019-08-01)

Reporter-ChIP-nexus reveals strong contribution of the Drosophila initiator sequence to RNA polymerase pausing
Dahkki: Wanqing Shao, et al.
Almmustuhtton: (2019-04-01)

The elemental mechanism of transcriptional pausing
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Almmustuhtton: (2019-01-01)

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Almmustuhtton: (1993)

RNA polymerase II pausing downstream of core histone genes is different from genes producing polyadenylated transcripts.
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Almmustuhtton: (2012-01-01)

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Transcription Pause and Escape in Neurodevelopmental Disorders
Dahkki: Kristel N. Eigenhuis, et al.
Almmustuhtton: (2022-05-01)

Tyrosine 1-phosphorylated RNA polymerase II transcribes PROMPTs to facilitate proximal promoter pausing and induce global transcriptional repression in response to DNA damage
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Almmustuhtton: (2024)

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RNA Polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation
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Almmustuhtton: (2023)

RNA polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation.
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Almmustuhtton: (2023)

Grounded: Transcriptional Pausing in Naive mESCs
Dahkki: Guenther, Matthew G., et al.
Almmustuhtton: (2014)

YEAST RNA POLYMERASE-II TRANSCRIPTION - ENZYMATIC-ACTIVITIES OF GENERAL INITIATION-FACTORS, 3-D STRUCTURES OF INITIATION-FACTORS AND RNA-POLYMERASE, AND MECHANISM OF TRANSCRIPTIONAL ACTIVATION
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Almmustuhtton: (1992)

Structures of co-transcriptional RNA capping enzymes on paused transcription complex
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Almmustuhtton: (2024-05-01)

Definition of transcriptional pause elements in fission yeast.
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Almmustuhtton: (1999)

c-Myc regulates transcriptional pause release
Dahkki: Rahl, Peter B., et al.
Almmustuhtton: (2012)