Molecular basis of class A β-lactamase inhibition by relebactam
β-Lactamase production is the major β-lactam resistance mechanism in Gram-negative bacteria. β-Lactamase inhibitors (BLIs) efficacious against serine β-lactamase (SBL) producers, especially strains carrying the widely disseminated class A enzymes, are required. Relebactam, a diazabicyclooctane (DBO)...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Published: |
American Society for Microbiology
2019
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