Probing the agonist binding pocket in the nicotinic acetylcholine receptor: a high-resolution solid-state NMR approach.

Acetylcholine, the agonist for the nicotinic acetylcholine receptor, has been observed directly when bound specifically to its binding site in the fully functional receptor-enriched membranes from Torpedo nobiliana. High-resolution solid-state, magic angle spinning 13C NMR methods have been used to...

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Bibliographic Details
Main Authors: Williamson, P, Gröbner, G, Spooner, P, Miller, K, Watts, A
Format: Journal article
Language:English
Published: 1998