No evidence for allelic association of a human CTLA-4 promoter polymorphism with autoimmune thyroid disease in either population-based case-control or family-based studies.

OBJECTIVE: The cytotoxic T lymphocyte associated-4 (CTLA-4) gene is a candidate for T-cell mediated autoimmune disease and polymorphism has been reported to be associated with both type 1 diabetes and autoimmune thyroid disease. A previously unreported polymorphism of the promoter region of the hum...

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Bibliographic Details
Main Authors: Heward, J, Allahabadia, A, Carr-Smith, J, Daykin, J, Cockram, C, Gordon, C, Barnett, A, Franklyn, J, Gough, S
Format: Journal article
Language:English
Published: 1998