Sickness behaviour is induced by a peripheral CXC-chemokine also expressed in multiple sclerosis and EAE.

Non-CNS chemokine production may contribute to previously unrecognised components of Multiple Sclerosis (MS) pathology. Here we show that IL-8, a neutrophil chemoattractant, is significantly increased in serum from individuals with MS, and that the rodent homolog of IL-8 (CXCL1) is expressed in the...

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Bibliographic Details
Main Authors: Campbell, S, Meier, U, Mardiguian, S, Jiang, Y, Littleton, E, Bristow, A, Relton, J, Connor, T, Anthony, D
Format: Journal article
Language:English
Published: 2010