Sickness behaviour is induced by a peripheral CXC-chemokine also expressed in multiple sclerosis and EAE.
Non-CNS chemokine production may contribute to previously unrecognised components of Multiple Sclerosis (MS) pathology. Here we show that IL-8, a neutrophil chemoattractant, is significantly increased in serum from individuals with MS, and that the rodent homolog of IL-8 (CXCL1) is expressed in the...
Main Authors: | , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2010
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