Development of CRISPR gene therapy for retinal degenerations

Development of CRISPR gene therapy for retinal degenerations

<p>Inherited retinal degenerations (IRDs) are a leading cause of blindness, caused by mutations in genes leading to dysfunction and death of cells in the outer retina. Gene-supplementation therapies using adeno-associated viral (AAV) vectors have been developed, however, they are limited to th...

書誌詳細
第一著者:	Fry, LE
その他の著者:	MacLaren, R
フォーマット:	学位論文
言語:	English
出版事項:	2021
主題:	Genetics Retina Eye

類似資料

Developing gene therapy for inherited retinal degenerations
著者:: Yusuf, IH
出版事項: (2022)

Retinal Cell Regeneration by Stem Cells
著者:: Fatemeh Nazem-Roaya, 等
出版事項: (2015-05-01)

Retinal dysplasia in the crab-eating fox (Cerdocyon thous)
著者:: Roberta Renzo, 等
出版事項: (2016-10-01)

Formation of visual images : studies of stabilized retinal images/
著者:: 447023 Zinchenko, V. P., 等
出版事項: (1972)

Multiplexed CRISPR/Cas9 Targeting of Genes Implicated in Retinal Regeneration and Degeneration
著者:: Arife Unal Eroglu, 等
出版事項: (2018-08-01)

Comparing optogenetic approaches to visual restoration in a model of retinal degeneration
著者:: Gilhooley, MJ
出版事項: (2019)

Retinal and Choroidal Thickness in Myopic Young Adults
著者:: Enrique J. Fernández, 等
出版事項: (2022-05-01)

Retinal and vitreous metastases from hepatocholangiocarcinoma
著者:: Anna Praidou, 等
出版事項: (2017-06-01)

Widefield imaging of retinal and choroidal tumors
著者:: Natalia F. Callaway, 等
出版事項: (2019-12-01)

Microglia in Retinal Degeneration
著者:: Khalid Rashid, 等
出版事項: (2019-08-01)

The Ocular Gene Delivery Landscape
著者:: Bhubanananda Sahu, 等
出版事項: (2021-08-01)

Retinal Adaptation in Response to Light and Dark Regimes in the Oriental Armyworm <i>Mythimna separata</i> (Lepidoptera: Noctuidae)
著者:: Qing-Xiao Chen, 等
出版事項: (2024-02-01)

Alterations in kainate receptor and TRPM1 localization in bipolar cells after retinal photoreceptor degeneration
著者:: Jacqueline eGayet-Primo, 等
出版事項: (2015-12-01)

Locomotion Index and Retinal Thickness of the Eye Anguilla bicolor bicolor in its Developmental Stage
著者:: Nur Indah Septriani, 等
出版事項: (2023-01-01)

Ocular Barriers and Their Influence on Gene Therapy Products Delivery
著者:: Bastien Leclercq, 等
出版事項: (2022-05-01)

Nailfold capillaroscopy and retinal findings in patients with systemic sclerosis: Is there an association?
著者:: Deepak Jakhar, 等
出版事項: (2020-01-01)

Increasing Eye Injuries Following Exposure to Laser Beams, the Silent Epidemic
著者:: Masood Bagheri
出版事項: (2023-09-01)

Cellular and Molecular Triggers of Retinal Regeneration in Amphibians
著者:: Yuliya V. Markitantova, 等
出版事項: (2023-09-01)

Long-chain and very long-chain polyunsaturated fatty acids in ocular aging and age-related macular degeneration
著者:: Aihua Liu, 等
出版事項: (2010-11-01)

Retinal fluorescein contrast arrival time of young patients with the hepatosplenic form of the Schistosomiasis mansoni
著者:: Ana Catarina Delgado de Souza, 等
出版事項: (2002-10-01)

Retinal ganglion cells undergo cell type—specific functional changes in a computational model of cone-mediated retinal degeneration
著者:: Aiwen Xu, 等
出版事項: (2023-05-01)

Differentially-expressed opsin genes identified in Sinocyclo-cheilus cavefish endemic to China
著者:: Fanwei MENG, Yahui ZHAO, John H. POSTLETHWAIT, Chunguang ZHANG
出版事項: (2013-04-01)

Ablation of pigment epithelium-derived factor receptor (PEDF-R/Pnpla2) causes photoreceptor degeneration
著者:: Alexandra Bernardo-Colón, 等
出版事項: (2023-05-01)

Microglia are not required for prion-induced retinal photoreceptor degeneration
著者:: James F. Striebel, 等
出版事項: (2019-03-01)

Stem cell transplantation for retinal degeneration: current status and future prospects
著者:: LIU Yong
出版事項: (2019-02-01)

Comprehensive characterization of fetal and mature retinal cell identity to assess the fidelity of retinal organoids
著者:: Hani Jieun Kim, 等
出版事項: (2023-01-01)

Immunological responses to retinal gene therapy
著者:: Chandler, L
出版事項: (2021)

Eye retinal changes under the influence of chromium ions
著者:: Y. V Kuzenko, 等
出版事項: (2018-02-01)

Retinal changes in an ATP-induced model of retinal degeneration
著者:: Felix Peter Aplin, 等
出版事項: (2016-04-01)

Current management of inherited retinal degenerations in Portugal (IRD-PT survey)
著者:: João Pedro Marques, 等
出版事項: (2024-09-01)

Synaptic remodeling of neuronal circuits in early retinal degeneration
著者:: Florentina eSoto, 等
出版事項: (2015-10-01)

Global Jitter Motion of the Retinal Image Dynamically Alters the Receptive Field Properties of Retinal Ganglion Cells
著者:: Akihiro Matsumoto, 等
出版事項: (2019-09-01)

Gene-agnostic therapeutic approaches for inherited retinal degenerations
著者:: Molly C. John, 等
出版事項: (2023-01-01)

Opportunities for CRISPR/Cas9 Gene Editing in Retinal Regeneration Research
著者:: Leah J. Campbell, 等
出版事項: (2017-11-01)

TDP-43 as a potential retinal biomarker for neurodegenerative diseases
著者:: Margit Glashutter, 等
出版事項: (2025-02-01)

Cell Ferroptosis: New Mechanism and New Hope for Retinitis Pigmentosa
著者:: Ming Yang, 等
出版事項: (2021-08-01)

Corrigendum: Global Jitter Motion of the Retinal Image Dynamically Alters the Receptive Field Properties of Retinal Ganglion Cells
著者:: Akihiro Matsumoto, 等
出版事項: (2020-03-01)

Towards an In Vitro Retinal Model to Study and Develop New Therapies for Age-Related Macular Degeneration
著者:: Beatrice Belgio, 等
出版事項: (2021-01-01)

Retinal Map of Peripheral Retinal Degenerations and Tears. Part 2. Non-rhegmatogenous Chorioretinal Degenerations
著者:: V. A. Shaimova, 等
出版事項: (2024-10-01)

Involvement of neuronal nitric oxide synthase in N-methyl-N-nitrosourea-induced retinal degeneration in mice
著者:: Yoshiki Koriyama, 等
出版事項: (2015-03-01)