High level transcription of the complement regulatory protein CD59 requires an enhancer located in intron 1.

CD59 is a complement regulatory protein and may also act as a signal-transducing molecule. CD59 transgenic mice have been generated using a CD59 minigene (CD59 minigene-1). Although this minigene contained a 4.6-kilobase pair 5'-flanking region from the human CD59 gene as a promoter, the expres...

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Bibliographic Details
Main Authors: Tone, M, Diamond, L, Walsh, L, Tone, Y, Thompson, SA, Shanahan, E, Logan, J, Waldmann, H
Format: Journal article
Language:English
Published: 1999