High level transcription of the complement regulatory protein CD59 requires an enhancer located in intron 1.
CD59 is a complement regulatory protein and may also act as a signal-transducing molecule. CD59 transgenic mice have been generated using a CD59 minigene (CD59 minigene-1). Although this minigene contained a 4.6-kilobase pair 5'-flanking region from the human CD59 gene as a promoter, the expres...
Prif Awduron: | Tone, M, Diamond, L, Walsh, L, Tone, Y, Thompson, SA, Shanahan, E, Logan, J, Waldmann, H |
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Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
1999
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Eitemau Tebyg
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Transfection of human CD59 complementary DNA into rat cells confers resistance to human complement.
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