Osteoblasts stimulate osteoclastogenesis via RANKL expression more strongly than periodontal ligament cells do in response to PGE2

Objective: Periodontal ligament cells (PDLs) produce prostaglandin E 2 (PGE2) in response to orthodontic force. PGE2 is a potent osteoclast-inducing factor that induces the receptor activator of nuclear factor-κB ligand (RANKL). Some studies reported that PDLs express RANKL in response to mechanical...

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Bibliographic Details
Main Authors: Mayahara, K, Yamaguchi, A, Takenouchi, H, Kariya, T, Taguchi, H, Shimizu, N
Format: Journal article
Language:English
Published: 2012