Synthesis of Imidazolidin-4-ones via a Cytochrome P450-Catalyzed Intramolecular C−H Amination
Expanding Nature’s catalytic repertoire to include reactions important in synthetic chemistry opens new opportunities for biocatalysis. An intramolecular C–H amination route to imidazolidin-4-ones via α-functionalization of 2-aminoacetamides catalyzed by evolved variants of cytochrome P450BM3 (CYP10...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Published: |
American Chemical Society
2016
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