Synthesis of Imidazolidin-4-ones via a Cytochrome P450-Catalyzed Intramolecular C−H Amination

Synthesis of Imidazolidin-4-ones via a Cytochrome P450-Catalyzed Intramolecular C−H Amination

Expanding Nature’s catalytic repertoire to include reactions important in synthetic chemistry opens new opportunities for biocatalysis. An intramolecular C–H amination route to imidazolidin-4-ones via α-functionalization of 2-aminoacetamides catalyzed by evolved variants of cytochrome P450BM3 (CYP10...

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Bibliographic Details
Main Authors:	Ren, X, O'Hanlon, J, Morris, M, Robertson, J, Wong, L
Format:	Journal article
Published:	American Chemical Society 2016

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