Enantiopure bicyclic piperidinones: Stereocontrolled cycloadditions

The cycloadditions of a [4.3.0]-bicyclic α,β-unsaturated lactam, derived from 6-oxopipecolic acid, have been investigated. Although yields are modest, diastereoselectivity is high; reasons for the low reactivity are postulated, based on experimental observations and molecular modelling. © 2005 Benth...

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Bibliographic Details
Main Authors: Brewster, A, Broady, S, Glenn, E, Hermitage, SA, Hughes, M, Moloney, M, Woods, G
Format: Journal article
Language:English
Published: 2005