Synthesis of (+/-)-secosyrin 1 and a formal synthesis of (-)-secosyrin 1.
[reaction: see text] A short synthesis of (+/-)-secosyrin 1 is presented that starts from an electron-deficient furan; reductive alkylation under Birch conditions gives rapid access to the natural product skeleton. Two aspects of stereoselectivity are explored, the first being directed dihydroxylati...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2004
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