Synthesis, oligonucleotide incorporation and fluorescence properties in DNA of a bicyclic thymine analogue

Fluorescent base analogues (FBAs) have emerged as a powerful class of molecular reporters of location and environment for nucleic acids. In our overall mission to develop bright and useful FBAs for all natural nucleobases, herein we describe the synthesis and thorough characterization of bicyclic th...

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Bibliographic Details
Main Authors: Lawson, CP, Füchtbauer, AF, Wranne, MS, Giraud, T, Floyd, T, Dumat, B, Andersen, NK, El-Sagheer, A, Brown, T, Gradén, H, Wilhelmsson, LM, Grøtli, M
Format: Journal article
Language:English
Published: Nature Publishing Group 2018