HIV-1-CD4-coreceptor interactions in virus binding and neutralization

Míreanna comhchosúla

• Inhibition of virus attachment to CD4+ target cells is a major mechanism of T cell line-adapted HIV-1 neutralization.
  de réir: Ugolini, S, et al.
  Foilsithe / Cruthaithe: (1997)
• Selective HIV-1-induced downmodulation of CD4 and coreceptors.
  de réir: Chenine, A, et al.
  Foilsithe / Cruthaithe: (2000)
• Interactions among HIV gp120, CD4, and CXCR4: dependence on CD4 expression level, gp120 viral origin, conservation of the gp120 COOH- and NH2-termini and V1/V2 and V3 loops, and sensitivity to neutralizing antibodies.
  de réir: Mondor, I, et al.
  Foilsithe / Cruthaithe: (1998)
• Neutralization of human immunodeficiency virus type 1 by antibody to gp120 is determined primarily by occupancy of sites on the virion irrespective of epitope specificity.
  de réir: Parren, P, et al.
  Foilsithe / Cruthaithe: (1998)
• Antibody neutralization of HIV-1 and the potential for vaccine design.
  de réir: Sattentau, Q, et al.
  Foilsithe / Cruthaithe: (1999)