Asymmetric synthesis of the allocolchicinoid natural product N-acetylcolchinol methyl ether (suhailamine), solid state and solution phase conformational analysis

An asymmetric synthesis of the allocolchicinoid N-acetylcolchinol methyl ether (NCME) from 3-methoxybenzaldehyde is reported. Comparison of 1H and 13C NMR spectroscopic data obtained for this sample of NCME provide further evidence for the assertion that this compound is congruous with the natural p...

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Bibliographic Details
Main Authors: Davies, S, Fletcher, A, Roberts, P, Thomson, J, Yeung, A
Format: Journal article
Language:English
Published: Elsevier 2019