Avirulent strains of Toxoplasma gondii infect macrophages by active invasion from the phagosome.

Unlike most intracellular pathogens that gain access into host cells through endocytic pathways, Toxoplasma gondii initiates infection at the cell surface by active penetration through a moving junction and subsequent formation of a parasitophorous vacuole. Here, we describe a noncanonical pathway f...

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Bibliographic Details
Main Authors: Zhao, Y, Marple, A, Ferguson, D, Bzik, D, Yap, G
Format: Journal article
Language:English
Published: National Academy of Sciences 2014