A novel assay for the identification of NOTCH1 PEST domain mutations in chronic lymphocytic leukemia

A novel assay for the identification of NOTCH1 PEST domain mutations in chronic lymphocytic leukemia

<strong>Aims.</strong> To develop a fast and robust DNA-based assay to detect insertions and deletions mutations in exon 34 that encodes the PEST domain of NOTCH1 in order to evaluate patients with chronic lymphocytic leukemia (CLL). <br> <strong>Methods.</strong> We de...

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Bibliographic Details
Main Authors: Campregher, PV, Petroni, RC, Muto, NH, Sitnik, R, de Carvalho, FP, Bacal, NS, Velloso, EDRP, Oliveira, GB, Pinho, JRR, Torres, DC, Braga Mansur, M, Hassan, R, Lorand-Metze, IGH, Chiattone, CS, Hamerschlak, N, Mangueira, CLP
Format: Journal article
Language:English
Published: Hindawi Publishing Corporation 2016

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