Cancer predisposition syndromes: lessons for truly precision medicine

Cancer predisposition syndromes are typically uncommon, monogenic, high-penetrance disorders. Despite their rarity, they have proven to be highly clinically relevant in directing cancer prevention strategies. As such, they share notable similarities with an expanding class of low-frequency somatic m...

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Autori principali: Glaire, M, Brown, M, Church, D, Tomlinson, I
Natura: Journal article
Pubblicazione: John Wiley & Sons Ltd 2016