A stretched conformation of DNA with a biological role?
We have discovered a well-defined extended conformation of double-stranded DNA, which we call Σ-DNA, using laser-tweezers force-spectroscopy experiments. At a transition force corresponding to free energy change ΔG = 1·57 ± 0·12 kcal (mol base pair)−1 60 or 122 base-pair long synthetic GC-rich seque...
Main Authors: | , , , , , , , |
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Format: | Journal article |
Published: |
Cambridge University Press
2017
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