Overcoming chloroquine resistance in malaria: Design, synthesis and structure-activity relationships of novel chemoreversal agents.

Malaria remains a significant infectious disease with even artemisinin-based therapies now facing resistance in the field. Development of new therapies is urgently needed, either by finding new compounds with unique modes of action, or by reversing resistance towards known drugs with 'chemosens...

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Bibliographic Details
Main Authors: Boudhar, A, Ng, X, Loh, C, Chia, W, Tan, Z, Nosten, F, Dymock, B, Tan, K
Format: Journal article
Language:English
Published: Elsevier 2016